منابع مشابه
Towards an HIV cure
Given the challenge of delivering complex, expensive and potentially harmful antiretroviral therapy (ART) on a global level, there is intense interest in the development of short-term, well-tolerated regimens that allow individuals to interrupt therapy indefinitely without experiencing a rebound in viremia. This so-called "cure" or "remission" might be due to complete eradication of all replica...
متن کاملAre Microbes Optimal Strategists?
In an earlier peper [ I ] on the experimental evd~~iit ioll of cyhernetic models for 1)acterial growth on multiple substrates, we presented certain hasic postulates 1)ased on all existing experimental literatnre known to us that all models for bacterial growth in a multisuhstrate environment must satisfy. At the suggestion of one of the reviewers of that paper, we are presenting an analysis of ...
متن کاملControversies in HIV cure research
BACKGROUND Antiretroviral therapy significantly reduces HIV viral burden and prolongs life, but does not cure HIV infection. The major scientific barrier to a cure is thought to be the persistence of the virus in cellular and/or anatomical reservoirs. DISCUSSION Most efforts to date, including pharmaco, immuno or gene therapy, have failed to cure patients, with the notable exception of a stem...
متن کاملCombined approaches for HIV cure.
PURPOSE OF REVIEW A serious effort has begun to develop therapies that may be capable of eradicating established HIV infection in man. Because of the biological complexity of HIV infection that persists despite potent antiretroviral therapy, it is widely believed that if such therapies can be developed they will involve complex, multimodality approaches. We highlight some of the recent studies ...
متن کاملHype and the HIV cure.
Atul Gawande, the surgeon and author, was one of the first to react. “This is huge, stunning, world changing,” he tweeted, linking to a story of a “startling development” in the New York Times titled “In a medical first, a baby with HIV is deemed cured.” The article explained how a baby in the United States had been treated with antiretrovirals 30 hours after birth, and by 18 months of age the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: AIDS
سال: 2017
ISSN: 0269-9370
DOI: 10.1097/qad.0000000000001268